Baseline Estradiol Level: This blood test is obtained 1 to 2 days before stimulation medications start. This test is confirm that the patients estradiol hormone is <50. The estradiol hormone must be <50 to start stimulation. This applies to all conventional patients and egg donors. If the patient starts her period approximately 4 days prior to this scheduled baseline estradiol blood test, she does NOT need to have the estradiol level checked. By starting her period in this time frame indicates a low estradiol hormone. Thus, she can start her stimulation protocol as per her calendar.
This ultrasound is performed 1 to 2 days prior to the start of injections. This ultrasound may apply to all recipients, surrogates or any patient undergoing a frozen embryo transfer cycle in addition to patients undergoing a conventional IVF cycle. In some cases a baseline estradiol blood test is performed instead of the baseline ultrasound depending upon the location of the patient and the availability of the physician. This baseline ultrasound assesses the ovaries for cysts. The ovaries must be free of ovarian cysts to start the injections.
FDA Testing: As of May 2005, the FDA requires that all cycles using an egg donor (anonymous or known) must repeat infectious screening within 30 days of the Embryo Transfer. All sperm sources when using a surrogate must also repeat this testing. The testing is performed at the baseline estradiol or baseline ultrasound time during the cycle. The testing that must to be repeated for all egg donors are: HIV 1&2, HTLV 1&2, Hepatitis Bsag, Hepatitis B core AB, Hepatitis CAB, RPR/VDRL, Cervical Gonorrhea/Chlamydia. The testing that must be repeated for all sperm sources when using a surrogate are: HIV 1&2, HTLV 1&2, Hepatitis Bsag, Hepatitis Bcore AB, Hepatitis CAB, RPR/VDRL, urine GC/Chlamydia.
IMPORTANT: All results of repeat infectious testing must be back and negative before the Embryo Transfer. If results are not back or abnormal the embryos will NOT be transferred.